Abstract： Prefabricated piers are widely used in the field of bridge construction and are often affected by accidental explosions or terrorist attacks． In order to study the influence law of the damage factors of prefabricated bridge piers under explosion load，a numerical model of the prefabricated bridge piers under near-field explosion load has been established by ANSYS． Based on the residual bearing capacity of bridge piers，the damage parameter D is proposed as the anti-explosion index． The influence of five damage factors，including the explosive equivalent，the distance from the explosion center，the initial prestress，the number of segments and the setting of shear keys，on the damage degree of bridge piers is analyzed． On this basis，grey correlation analysis method is used to measure the degrees of correlation and contribution among the damage factors． The results show that the comprehensive reduction rates of failure parameter D are 32． 1% and 29． 6% by increasing the initial prestress and setting shear keys between segments，which can effectively reduce the damage of the piers and have a good correlation with the blast resistance of prefabricated piers． However，increasing the shear key height and segment number to 12% and 7． 2% has a small effect on pier damage． The order from largest to smallest of the five factors in the correlation degree on the damage of the fabricated bridge piers under blast loading is: TNT equivalent，blast center distance，initial tensile prestress，shear key setting and segment number． In the anti-explosion design of prefabricated bridge piers，the factors of large correlations such as increasing the initial tensile prestress and setting shear keys can be given priority． The grey correlation analysis method has certain reference value for the analysis of damage factors of prefabricated bridge piers under explosive load．