Abstract： In order to study the influence of blasting vibration on the stability of permanent slopes in an open-pit mine，this paper takes three pits in the Kamoya-Kazibizi mine as the research object，and compares the effects of blasting vibrations on the stability of the slopes with different rock characteristics． By collating the measured blasting vibration data，the maximum charge per delay and the distances from the measuring points to the center of the blast source，the blast vibration attenuation law and curve are obtained by regression analysis with a power function，which can be used to predict future blasting vibrations． In order to obtain the influence of the distance from the measuring point to the center of the blast source and the maximum charge per delay on the vibration velocity，the distance and charge are taken as the influence factor，and the blasting vibration velocity is taken as the dependent variable． Based on the vibration velocity calculated according to the fitted blasting vibration formula of each pit，nine groups of experimental schemes are designed． Using SPSS software to carry out variance analysis，it is concluded that the distance between the measuring point and the center of the blast source is highly sensitive to the blasting vibration velocity， and has a greater impact on the mine slope vibration． Therefore，for the soft rock slopes of Kazibizi mine and East No． 2 mine，2 ～ 3 rows of holes are reserved as a non-blasting area，and mechanical excavation is used to trim the slopes． For the medium hard rock slope of South No． 2 mine，pre-split blasting is used to reduce the impact of blasting vibration on the slope stability． The research results have reference and application value for other open-pit coppercobalt mines in Congo．